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S1A indicated a dominant role of intestinal miRNAs in regulating L1 starvation survival. We used a dual-color 3′UTR reporter system (18) to test the computational, prediction-based hypothesis that the 3′UTRs of age-1 and unc-31 are directly regulated by miR-71 (Fig. 3B and Materials and Methods). Among these potential miRNA targets, the predicted miR-71–targeting sites in the 3′UTRs of age-1 and…
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“What is most difficult on Mia is the inability to focus or think deeply for long periods of time,” says her father. It’s hard, and she’s frustrated that she can’t run and play. “I’m able to confide in her about what’s going on in my life and can work things out. Mia is also grateful for her care and is…
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In countries such as China and Japan, the only way to gamble legally is through government-ran lotteries or casinos. Regarding youths who gamble, almost 50% of them report some form of gambling severe enough to be classified as problematic by the DSM. Additionally, many youths begin gambling before the age of 18, which correlates with the psychological etiologies of risk-taking…